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The painkiller Bextra was taken
off the market Thursday, and the government wants
similar prescription drugs to carry the strongest
possible warnings about increased risk of heart
attack and stroke among the millions of people
who rely on them.
This morning, the U.S. Food and
Drug Administration announced new labeling for
a broad swath of arthritis pain drugs, including
Advil, Aleve and Motrin. Pfizer's blockbuster
Celebrex will get the most serious type of warning
the FDA can level, and Bextra, another Pfizer
arthritis drug, will be removed from the market
in the U.S. and in Europe.
The drug bextra was taken off the
market today after the Food & Drug Administration
called for the withdrawal of the arthritis pain
medication — a member of the family of painkillers
that includes Vioxx.
The FDA has asked the drug company
Pfizer to withdraw the arthritis drug Bextra from
the market because it says the risks of the drug
outweigh the benefits.
Pfizer has agreed to suspend sales
and marketing of Bextra in the U.S. But in a new
release, the company says "it respectfully
disagrees with the FDA's position regarding the
overall risk benefit profile of Bextra."
Pfizer says it will talk with the FDA about ways
to let the company restore Bextra's availability
to doctors and patients. But for now, Pfizer advises
patients to "stop taking Bextra and contact
their physicians about other appropriate treatment
options.
The incidence of heart attacks and
strokes among patients given Pfizer's painkiller
Bextra was more than double that of those given
placebos, according to preliminary results of
a study presented yesterday at the American Heart
Association meeting in New Orleans.
Drug manufacturer Pfizer said Friday
that its Bextra drug, seen as an alternative to
Merck's Vioxx arthritis medication, may raise
heart attack risk in high-risk bypass surgery
patients.
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